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  Human Liver S9 Fraction-50 Donors (0.5 mL), Product Code: HC-0018



 
Product Spec Sheet

Price: $44.00


Product Code: HC-0018

Description
 
Lifeline’s Pooled Human Liver S9 Fractions provide a fully characterized, relevant, reliable and reproducible in vitro tool.  Pooled Liver S9 Fractions from pools of 50 donors gives an accurate and economic method of deriving a population representation that may be sed to describe the metabolic profile of a drug or drug candidate in high-throughput assays as well as the following other uses:

• Conduct studies of metabolic stability (% of original drug remaining over time)
• Identify which cytochrome P450 (CYP) enzymes oxidize a drug candidate and which UDP-glucuronosyltransferase (UGT) enzymes are responsible for glucuronidation
• Identify, quantify and characterize drug metabolites
• Describe  a drug’s metabolic pathways
• Identify inhibition of cytochrome P450 (CYP) enzymes

For more information about this product, please visit our product specification sheet HERE.

For more product information, please visit our product specifications page HERE.

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